Furthermore, ltFM and these indices were also capable of predicting SLE flares in the participants, with the probability (P) of SLE flare calculated using the logistic regression formula:P = 1/(1 + e−z), where z = 1.821 × ltFM + 0.012 × anti-dsDNA − 3.247 × C3 − 0.089 (Figure 4, Table 6). The gene discussed is C3; the disease is systemic lupus erythematosus.