MYC and cancer: We subjected the differentially expressedtranscripts to gene set enrichment analysis (GSEA) using the HallmarkPathways collection from the Molecular Signatures Database (Figure B), revealing severalpathways associated with cancer or tumor metastasis that were significantlyenriched with the gene sets regulated by compound 1 (apicaljunction, mitotic spindle, epithelial–mesenchymal transition(EMT), MYC targets, and KRAS signaling).