The importance of these functions is underscoredby disease phenotypes such as muscular dystrophies, lipodystrophy,and various cancers linked to the dysfunction of caveolae.−,  Caveolae are formed primarily by the coordinated actions of threecaveolin and four cavin proteins. Thepresent study focuses on the 8S complex, an oligomeric form of caveolin-1(CAV1). The gene discussed is CAV1; the disease is muscular dystrophy.