The former, as a stabilizer of β-amyloid protein, may suggest the potential impact of edible oil intake on the risk of neurodegeneration (68); the downregulation of 5′-3′ exonuclease PLD3 in the Alzheimer’s disease model is in contrast to its upregulation in this study, suggesting that dietary components may be involved in neuroprotection or pathological processes by regulating the processing of amyloid precursor protein. Here, PLD3 is linked to early-onset autosomal dominant Alzheimer disease.