However, previous studies have shown that cardiomyopathy patients carrying a causative mutation in the LMNA gene have a wide range of onset ages and can develop the disease any time from adolescence to old age, with an average age of 40 years; penetrance increases with age, with 50% penetrance in autosomal dominant patients aged 30–40 years and 90% penetrance in patients aged >40 years (25). The gene discussed is LMNA; the disease is cardiomyopathy.