BCR-ABL positive chronic myelogenous leukemia (CML) is the commonest entity encountered in clinical practice in the Asian subcontinent and is usually associated with the BCR-ABL1 fusion gene present on the Philadelphia chromosome t(9;22) encoding for proteins which have persistently enhanced tyrosine kinase activity [2]. This evidence concerns the gene BCR and chronic myelogenous leukemia, BCR-ABL1 positive.