NFE2L2 and diabetes mellitus: Amygdalin, the main component of [Prunus persica (L.)Batsch], protects against high-glucose-induced ferroptosis and oxidative stress in retinal endothelial cells by activating the NRF2/antioxidant response element (ARE) signaling pathway, highlighting its therapeutic potential in alleviating diabetes-related microvascular damage (Li S. et al., 2023).