Table 1 summarize the preoperative characteristics of these 60 patients. It shows that the tumor site of LAPD's patients was mainly Ampulla of Vater. The average Operation time and blood loss of the LAPD group are no significant differencesthe compared with the OPD group. The same results occurred in the other background characteristics and surgical outcomes between OPD and LAPD involving age, sex, weight, ALT, ALB, TB, hospital stay, pancreatic texture, pancreatic duct diameter and FRS. The gene discussed is GPT; the disease is neoplasm.