MAPT and Alzheimer disease: Additionally, the centiloid (CL) scale measured approximately 100 CL, suggesting at least mild-to-moderate AD and indicating advanced amyloid/tau accumulation in the brain in specific regions of interest (Fig. 1andTable 1).9, 10, 11, 12With a full understanding of her condition and the limited treatment options available, her family decided to proceed with pilot LVB surgery, providing informed consent for both the procedure and the use of her photos, videos, and medical records.