Univariable analysis revealed that the CA125 level (odds ratio [OR], 1.03 [95% CI: 1.01, 1.06]; P = 0.001), tumor size (OR, 1.05 [95% CI: 1.02, 1.09]; P = 0.001), and APTw_h3 values (OR, 7.99 [95% CI: 7.61, 9.78]; P < 0.001) were associated with LVSI positivity (Table 4). The gene discussed is MUC16; the disease is neoplasm.