Factors with statistical differences were included in the Logistic regression model, therapeutic efficacy was taken as the dependent variable (effective group =1, ineffective group =0), and indicators with statistical significance in clinical data (tumor size, number of liver metastases, TNM stage, differentiation degree, CEA, CA19-9, miR-122, miR-21, BMI and age) were taken as the independent variable. This evidence concerns the gene CEACAM5 and neoplasm.