Significant differences were found in age, BMI, serum miR-21 expression level (relative expression greater than 2.0, considered as a high expression state), miR-122 expression level (relative expression less than 0.5, considered as a low expression state), CA19-9, CEA, differentiation degree, TNM stage, the number of liver metastases, and tumor size (P<0.05). Here, CEACAM5 is linked to neoplasm.