Overexpression of a ATP13A2 orthologue in yeast was shown to impart zinc resistance (Kong et al., 2014); on a different note, an individual with a mutant of ATP13A2 was affected with Kufor-Rakeb syndrome, a disease with shared features of Parkinsonism (van Veen et al., 2014). The gene discussed is ATP13A2; the disease is Parkinsonism.