The panel concurs that managing ROD is essential before addressing CKD-induced osteoporosis. Effective ROD management helps stabilize bone metabolism, ensuring that subsequent osteoporosis treatments are more effective and tailored to the patient’s needs.Biochemical parameters like Calcium, Phosphate, Vitamin D and PTH can also be utilized.Bone biomarkers can be used to monitor that the patient is compliant to the treatment or not and to assess the effectiveness of treatment. The gene discussed is PTH; the disease is chronic kidney disease.