ALDOA and hepatocellular carcinoma: To explore the biological function of ALDOA in HCC, we detected the protein levels in six HCC cell lines and observed higher levels of ALDOA in Huh-7, MHCC97L, MHCC97H, and HCCLM3 cells, and similar levels in HHCC and HepG2 cells compared to normal liver THLE2 cells (Fig. 1A).