A genome-wide association study (GWAS) of ADRD that included AA participants in MVP and the Alzheimer’s Disease Genetics Consortium (ADGC) [10] identified genome-wide significant (GWS) associations with variants in genes previously linked to AD risk (apolipoprotein E (APOE), ABCA7, triggering receptor expressed on myeloid cells 2 (TREM2), CD2-associated protein (CD2AP)) and one novel gene roundabout guidance receptor 1 (ROBO1) [5]. The gene discussed is ROBO1; the disease is Alzheimer disease.