TARDBP and amyotrophic lateral sclerosis: Whereas mislocalization of RBPs other than TDP-43 is not frequently encountered in sporadic ALS (Honda et al, 2015; Tada et al, 2018; Tyzack et al, 2019), similar dysfunction of FUS, MATR3, and hnRNPA1 might also be evident while they remain in the nucleus.