Gruber et al. generated a caerulein-induced pancreatitis model in R26-LSL-YFP; LSL-KRASG12D; Ela1-CreERT2 mice to demonstrate that YAP and TAZ in acinar cells were required to induce ADM and PanIN formation in the context of pancreatitis [43]. Here, CELA1 is linked to pancreatitis.