In each case, levels varied following infection and the pattern differed between the groups, although both groups exhibited peaks at day 2 PI in CD69 + CD4+ (lean p = 0.0002 vs B and obese p = 0.0005 vs B) and CD69 + CD8 + T cells (lean p = 0.0003 vs B and obese p=<0.0001 vs B) and at day 3 PI in CD38 + CD4 + T cells (lean p = 0.0011 vs B and obese p=<0.0001 vs B). The gene discussed is CD4; the disease is infection.