FBL and posterior cortical atrophy: In this study, we selected nucleophosmin (NPM1) present in the GC region [23, 24] and fibrillarin (FBL) present in the DFC region [24, 25, 26] of the nucleolus and analyzed their cellular localization, expression in PCa patient specimens, and role in regulating proliferation, migration and invasion, and nucleolar morphology.