IL21 and inflammatory bowel disease: In contrast, IBD tissue showed, compared with non‐IBD tissue, lower baseline secretion of IL‐31 (log2FC: −1.54), IL‐21 (log2FC: −0.38), granzyme B (log2FC: −0.71), and IL‐27 (log2FC: −0.79), reaching statistical significance for IL‐31 (Figure 2B; Table S3).