LPS‐ and ConA‐induced functional immune responses in the tissue, with IBD tissue exhibiting increased levels of specific cytokines compared with non‐IBD tissue, including IL‐17F and IL‐21 after ConA‐stimulation, and IL‐22 as well as ENA‐78 following LPS‐stimulation. The gene discussed is IL17F; the disease is inflammatory bowel disease.