TNF and inflammatory bowel disease: In non‐IBD‐derived PCIS, ConA stimulation led to an increased secretion of general proinflammatory cytokines (e.g., IL‐1β, IL‐8, MCP‐1; log2FCs: 2.49–4.23), but also specific T cell‐associated cytokines (e.g., IL‐2, IFN‐γ, GM‐CSF, TNF‐α, IL‐17A, IL‐22, GzmA; log2FCs: 5.84–10.81) (Figure 2D).