LPS‐stimulated tissue from IBD patients showed, compared with LPS‐stimulated tissue from non‐IBD patients, increased secretion of mediators associated with the recruitment of innate immune cells and tissue repair, such as TNF‐α (log2FC: 4.4), IL‐22 (log2FC: 2.1), IL‐18 (log2FC: 2.4), TRAIL (log2FC: 1.85), and ENA‐78 (log2FC: 1.82), but, similar to unstimulated conditions, decreased secretion of IL‐31 (log2FC: −0.64). The gene discussed is IL31; the disease is inflammatory bowel disease.