YWHAG and infection: To investigate the role of 14-3-3γ in PRRSV infection, 14-3-3γ was knocked down using specific small interfering RNA (siRNA) in the PRRSV-permissive MARC-145 cell line (Fig. 1A), followed by infection with the HP-PRRSV strain TA-12 for 24, 36 and 48 hours.