LMNA and prediabetes syndrome: Malouf syndrome, characterized by a combination of dilated cardiomyopathy andhypergonadotropic hypogonadism, exhibits significant phenotypic heterogeneity, asevidenced by clinical variability among reported cases (4-6).Herein, we describe a 28-year-old female who presented with hypergonadotropichypogonadism, cardiac valvular calcification and valvulopathy, prediabetes,hyperlipidemia, and distinctive progeroid facial, skin, and skeletal features.Genetic testing revealed a heterozygous LMNA c.331G>Ap.(Glu111Lys) variant in exon 1.