proposed that variants in exon1 of the LMNA gene, which encodes the “rod domain” of the laminprotein, could lead to laminopathy clinically resembling Malouf syndrome due to thecombined presence of dilated cardiomyopathy and hypergonadotropic hypogonadism(8). This evidence concerns the gene LMNA and Hypergonadotropic hypogonadism.