Although some drugs showed higher risk of sleep paralysis, pruritis, skin diseases, sweating, peripheral edema, alanine aminotransferase increased, blood creatine phosphokinase increased, γ-Glutamyl transferase increased, hyperglycemia, and hypertension, these results were based on a limited number of studies with rare events and thus had high uncertainty (Appendix 11). The gene discussed is GPT; the disease is Hyperglycemia.