CD276 and central nervous system cancer: The ability of brain cancers to recruit mesenchymal cells and transform them to pericytes was first reported in rat gliomas, in which bone marrow-derived mesenchymal cells migrated to perivascular location and expressed pericity markers following intratumoral injection.33 To our knowledge, ours is the first evidence that glioma cells induce B7-H3 in this type of stem cells transformed to pericytes.