CpG site-specific comparisons showed that, within the male subgroup, significant differences between PD patients and controls were observed at CpG2, CpG4, CpG8, and CpG11 of the MAPT gene (p = 0.0223, p = 0.0185, p = 0.0346, and p = 0.00882, respectively) (Figure 7A). This evidence concerns the gene MAPT and Parkinson disease.