Conversely, the SCH treatment groups, particularly the high dose, demonstrated a marked elevation in mRNA expression of TNF‐α (p < 0.05) and TGF‐β (p < 0.05), alongside a decrease in mRNA expression of the anti‐inflammatory cytokines IL‐10 (p < 0.01) and IL‐4 (p < 0.0001) relative to the CTX group Figure 4C,D. This evidence concerns the gene TNF and spindle cell hemangioma.