For instance, serum exosomal long ncRNA FOXD2-AS1 has demonstrated promising diagnostic potential in colorectal cancer (CRC), achieving an overall AUC of 0.736 across all patients and an improved AUC of 0.758 specifically for early-stage CRC, highlighting its effectiveness as a stage-specific biomarker for early detection and clinical assessment. The gene discussed is FOXD2; the disease is colorectal carcinoma.