NCAM1 and rheumatoid arthritis: While resulting in closer proximity of APC and NK cell gates, the events in the red APC gate–used for all downstream analyses–remained clearly distinguishable (Figure 2B as well as Supplementary Figures S1, S2) with the contour overlay supporting that the CD56+HLA-DR+ population in RA originates from APC rather than NK cells (Figures 3D, F, black arrows).