CCR4 and ovarian cancer: (62), using flow cytometry, revealed that FOXP3- Treg infiltration in ovarian cancer correlates with CCR4 expression and enrichment of CCR4+, CCR5+, CXCR3+, and CXCR4+ T cells in both ascitic fluid and peripheral blood, linking this to elevated CCL22, CXCL9/10, and CXCL12 levels (Figure 1).