Similarly, AGD2 and AGD1 were reduced in the hypospadias group (69.9 ± 17.4 and 81.8 ± 19.4 mm, respectively) compared to the control group (79.8 ± 11.9 and 91.2 ± 12.8 mm, P < 0.05 for both). Here, MIR4435-2HG is linked to hypospadias.