NPPB and chronic kidney disease: Table 1 summarized the baseline characteristics of participants classified according to PLT dynamic changes. Compared to Class 1 (persistently low PLT count), participants in other classes had higher levels of age, RDW, BUN, Scr, BNP, DD, SOFA score, Lac, 24-h intake, and APACHE II scores, while ALB, FBG, 24-h output, and MAP levels were lower. Additionally, participants in other classes had a higher proportion of hypertension, urinary tract infection, males, CKD, history of stroke, shock, VAD, and MV compared to Class 1 (Table 1).