Reduction in the rate of decrease of eGFR as well as levels of C-reactive protein, IL-6, IS, and serum cholesterol is found to be lower in CKD patients fed with a higher fiber diet, >25 g/day, compared to the group with a lower fiber intake, <25 g/day, in the 18-months follow-up period of the 157 patients that participated in the study. The gene discussed is IL6; the disease is chronic kidney disease.