The results revealed that the tumor volume of the mice in the PTX group (31.95 ± 17.70 mm3, p < 0.001), IPI‐549 group (37.88 ± 12.59 mm3, p < 0.001), and IPI‐549+anti‐PD‐1 group (29.17 ± 9.38 mm3, p < 0.001) was significantly lower than that of the control group (131.93 ± 19.47 mm3), whereas the tumor volume of the mice in the anti‐PD‐1 group (81.69 ± 46.64 mm3, p = 0.105) also decreased, but the difference was not statistically significant. Here, PDCD1 is linked to neoplasm.