KRAS and cancer: Similarly, we also identified differences in isoform usage between KRAS-201 (KRAS4a) and KRAS-202 (KRAS4b), as well as between USO1-201 and USO1-204 (Fig. 5G and 5H), which have been reported as functionally relevant in cancer (Chen et al., 2021b; Dong et al., 2022).