Patients with plasma IL-8 levels in the highest quartile had a greater than three-fold odds of thrombosis or death (odds ratio [OR] = 3.12 [1.43 to 7.18], p = .005, Figure 3F), which remained significant following adjustment for age, sex, race/ethnicity, BMI, diabetes, COPD/asthma, and history of coronary artery disease or cancer (adjusted OR [adjOR] = 3.07 [1.25 to 8.06], p = .018, Figure 3F). This evidence concerns the gene CXCL8 and deep vein thrombosis.