Of note, other studies have found that IL-8, IL-6, CD40L, P-selectin, and TXB2 are significantly increased in the plasma of COVID-19 patients, further supporting their roles in the disease’s inflammatory and thrombotic pathways.10,11,18,27,31,37,38 While the following markers are not exclusively platelet-specific, they provide valuable insights into the overall inflammatory and thrombotic state during SARS-CoV-2 infection. The gene discussed is CXCL8; the disease is COVID-19.