Figure 10 A, denotes the quantitative RT-PCR analysis of pro-apoptotic and anti-apoptotic signaling genes such as MAPK, VEGFA, BCL-2, P-MAPK, HIF-1α and PDGF in tumor cells after treated with GEM, PU/CMC, PNIPAM-PU/CMC@GEM and PNIPAM-PU/CMC@GEM + NIR. The gene discussed is BCL2; the disease is neoplasm.