UPP1 and colorectal neoplasm: Furthermore, using Microenvironment Cell Populations-counter (MCP-counter) analysis to assess immune infiltrates in human tissue (Becht et al, 2016), the co-occurrence of increased UPP1 expression and a neutrophil signature was also reflected in transcriptomic data from human colorectal tumours, whilst no significant correlations were associated between UPP1 expression and T-cell signatures (Appendix Fig. S6B).