This indicated that expression of the adhesion molecule αM integrin (also known as CD11b) was consistently increased on the surface of neutrophils isolated from lungs of mice bearing mammary tumours, which were either orthotopically transplanted (KP tumour) or autochthonous (MMTV-PyMT), by comparison with the αM integrin surface expression detected in appropriate non-tumour-bearing controls (Fig. 3C,D). Here, ITGAM is linked to breast cancer.