PDX1 and pancreatic adenocarcinoma: For pancreatic adenocarcinoma (PDAC), Pdx1-Cre; LSL-KrasG12D/+; LSL-Trp53R172H/+ (KPC) mice were compared to Pdx1-Cre; LSL-KrasG12D/+; LSL-Trp53fl/+ (KPflC) mice.