RAG1 and neoplasm: We then activated OT-I T cells in 0.1 mM or 0.03 mM Met with either dimethylsulfoxide (DMSO) or TRAM-34 for 30 min, washed and cultured cells for an additional 24 h in 0.1 mM Met before transferring into B16-OVA tumor-bearing Rag1−/− mice (Extended Data Fig. 6k).