Through logistic LASSO regression analyses we identified a combination of four biomarkers (tPSA, epidermal growth factor (EGF), monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8)), which could be used to help triage symptomatic individuals at risk of PCa into low- and high-risk categories and improve clinical decision making20. The gene discussed is CXCL8; the disease is posterior cortical atrophy.