Loss of Kdm2a in sKO resulted in severe testicular atrophy at 26 d of age (Supplementary Fig. 4a), with a 72% decrease in testes to body weight ratio compared to Kdm2a2lox/+; Ngn3-Cre Ctrl (Supplementary Fig. 4b). Here, KDM2A is linked to Testicular atrophy.