PDE4B and pulpitis: For the phenotype Pulpal and apical diseases, two other loci in chromosomes 2 (near BCL11A) and 9 (near RMI1) (Table 3), and for the phenotype Pulpitis, three other loci in chromosomes 1 (near PDE4B), 9 (near NR4A3), and 17 (near VMP1 and TUBD1) (Table 3) were identified.