Long non-coding RNA linc00665 recruits EZH2 to bind the promoter region of cyclin-dependent kinase inhibitor 1C (CDKN1C), which inhibits the transcription of CDKN1C and influenced the sensitivity of NSCLC cells to cisplatin (Figure 2(a)) [25]. Here, CDKN1C is linked to non-small cell lung carcinoma.