STAT3 and cancer: Differential expression analysis between epithelial PDAC cancer cells with high ITGB3 expression (ITGB3-High; top 10% of cancer cells) and low ITGB3 expression (ITGB3-Low; bottom 10% of cancer cells) revealed that ITGB3 highly correlates with the other STAT3 target genes derived from our ChIP-seq data (Figure 2B).