Figure 6g shows the ratio (FC-fold change) of POST/PRE proteomic quantification at 3 (3M) and 6 months (6M) for different histone proteins: H2B, H3.1, H1T and H4. Figure 6h shows the Western blot analyses for H2B protein from the varicocele group before (PRE N = 4) and 3 (3 M N = 3) and 6 M N = 4) months after varicocelectomy. Densitometric analysis (Figure 6i) confirmed a significant decrease in this protein six months after surgery. Here, H2BC21 is linked to varicocele.