Also, 10 proteins from Table 1 (ACLY, ACSL4, ANXA2, ANXA3, COPD, EPIPL, TRFL, P3H1, KPYM, and SRSF5) were detected previously in the HepG2 cell line as having similar patterns to HCC proteoform (http://2de-pattern.pnpi.nrcki.ru/index.html accessed on 12 June 2025) [23]. This evidence concerns the gene ANXA3 and hepatocellular carcinoma.