According to UniProt, eleven proteins from Table 1 (ANXA1, ANXA2, FBLN3, FCN1, GALT2, TRFL, P3H1, PIGR, PROS, TSP1, and VWA1) are secreted and can be considered as better biomarker candidates for HCC. The gene discussed is VWA1; the disease is hepatocellular carcinoma.