To date, previous functional studies of Ptpmt1 have mainly focused on other cell systems, such as its essential role in cardiolipin biosynthesis in mouse embryonic fibroblasts (MEFs) in vitro [21], its regulation of proliferation and glucose metabolism in erythroleukemia cells [29], its promotion of cancer cell death [30], and its mutant disruption of cardiolipin metabolism leading to a neurodevelopmental syndrome [31]. The gene discussed is PTPMT1; the disease is cancer.