NTRK3 and amyotrophic lateral sclerosis: It was possible to identify gene annotations enriched among ALS-increased DEGs, ALS-decreased DEGs and genes near risk loci (p < 0.05 for each), which were related to sterol metabolism, plasma membrane, maturation of protein 3a, phospho-PLA2 pathway and NTRK3 signaling (Figure S26J,K,M).