Immunophenotyping and mutational profiling aid in differentiation: IgM MM lacks the MYD88 L265P mutation (>90% in WM), aiding differentiation, along with t(11;14), lytic lesions, and immunophenotypic markers (CD20−CD56−CD117−) [29,30,31,32,33]. The gene discussed is CD40LG; the disease is Miyoshi myopathy.