HSPA5 and cancer: Around the same time, Renata Pasqualini and Wadih Arap at the University of Texas MD Anderson Cancer Center, through fingerprinting the circulating repertoire of antibodies from cancer patients, identified the cell surface form of GRP78 (cs78) as a molecular target expressed in metastatic tumors with potential as a conduit for cancer specific delivery of cytotoxic agents while sparing normal tissues (58, 59).