SUCLG2 and colon adenocarcinoma: In COAD, low expression of SUCLG2 was associated with pathways such as cytosolic DNA-sensing pathway and regulation of autophagy (Figure 6C), while in READ, low expression of SUCLG2 was associated with pathways such as the toll-like receptor signaling pathway, antigen processing and presentation, and drug metabolism (Figure 6D).